Secondary & Tertiary NGS analysis - made for compatibility

API-driven connectivity for MH Guide

The MH Connector enables automated data submission and results retrieval and integrates seamlessly with MH Guide (CE-IVD) precision oncology workflows. Its APIs and NGS data adapters provide plug-and-play compatibility with enhanced connectivity for Archer Analysis users.

MH Connector - end-to-end, multi-modal data workflow within your existing NGS precision oncology workflow

Main benefits of MH Connector:

  • Seamless workflow integration – Easily connect your workflows with MH Guide using well-documented APIs to enable full automation from data submission to results retrieval.

  • Multi-modal biomarker support – Go beyond NGS and integrate and analyze diverse biomarkers, such as gene and protein expression, methylation, and gene wild-type status, within one unified framework.

  • Enhanced compatibility and connectivity – Benefit from plug-and-play compatibility with major secondary analysis platforms and advanced connectivity options for Archer Analysis, including automated data import and analysis initiation.

For teams using Archer Analysis and Archer NGS tumor panels the integration goes even deeper:

You can import gene expression data directly, view RNA expression plots (including expression per primer), see fusion imbalance, track the source assay per variant (RNA and/or DNA), jump to the sample in Archer Analysis, and review which assays were used for a case (e.g., DNA and RNA). Ordering analyses and downloading reports can be handled via API - by MH Connector or other tools outside MH Guide. For customers who are using or planning to implement e.g. Archer™ VARIANTPlex™ Complete Solid Tumor panels, this represents a meaningful step toward end-to-end, multi-modal support within your existing NGS tumor profiling workflow.

Experience MH Guide live!

You would like to experience MH Guide live or have questions about our tertiary analysis software?

The MH Connector + MH Guide tertiary NGS data analysis workflow is built for optimized compatibility with secondary analysis data from Archer Analysis.

MH Connector-MH Guide workflow

Get more information about MH Guide!

Disclaimer

MH Guide is a stand-alone Software as a Service (SaaS) used for in vitro examination of Next Generation Sequencing (NGS) data or genetic and molecular alteration data to provide information to help determine treatment options based on genetic biomarkers and medical guidelines for patients diagnosed with any cancer (solid and hematological tumors). MH Guide is used as an expert system for patient management by trained healthcare professionals qualified in genetics and oncology. Other diseases are out of scope.

MH Connector is for research use only (RUO). MH Connector is not for use in diagnostic procedures. Unless otherwise agreed to in writing, Molecular Health does not intend these products to be used in clinical applications and do not warrant fitness or suitability of the products for any clinical diagnostic use. The purchaser is solely responsible for all decisions regarding the use of the product and any associated regulatory or legal obligations. MH Connector is an optional external tool that integrates third-party NGS variant software solutions with MH Guide. MH Connector is provided by Molecular Health as Software as a Service (SaaS).

The legal manufacturer of MH Guide and MH Connector is Molecular Health GmbH, Kurfürsten-Anlage 21, 69115 Heidelberg, Germany.

 In the European Union (EU), MH Guide, including MH Guide, MH Guide/BRCA, and MH Guide/Mendel, is CE marked and registered as an in vitro diagnostic (IVD) medical device, Class C, under the IVD Regulation (EU) 2017/746. The conformity assessment procedure was conducted by the Notified Body TÜV SÜD Product Service GmbH; Identification Number: 0123. The purchaser is solely responsible for all decisions regarding the use of MH Guide and any legal and regulatory obligations.

Please note that using a reagent or component without CE-IVD marking in your diagnostic workflow will result in an in-house IVD (also known as laboratory-developed test [LDT]). According to Article 5(5) of Regulation (EU) 2017/746 on in vitro diagnostic medical devices (IVDR), these in-house IVDs must fulfill the general safety and performance requirements of the IVDR to meet regulatory requirements. Any gene panel with IVD (in vitro diagnostic) status, including in-house IVDs (LDTs), can be used in combination with MH Guide.

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